Top 10 Online Acute Care Nurse Practitioner (ACNP) Programs

7 Min Read Published March 17, 2025
Top 10 Online Acute Care Nurse Practitioner (ACNP) Programs

Becoming an acute care nurse practitioner can increase your salary and advance your career, but finding time to attend classes can be challenging. Fortunately, online ACNP programs accommodate working nurses, allowing you to keep working while advancing your education. 

Read on to see the top online acute care nurse practitioner programs for 2025. 

Popular Online Adult-Gerontology Nurse Practitioner (AGNP) Programs

Sponsored
Purdue Global

Whether you’re taking the first steps toward a nursing degree, seeking to advance as a nurse or want to hone your craft with specialized study, there’s a path for you at Purdue Global’s School of Nursing. Our programs were designed so that you can easily balance your lives at home and work with school - without sacrificing the rigor and cutting-edge curriculum of a quality nursing education.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Nationwide, but certain programs have state restrictions. Check with Purdue for details.

Grand Canyon University

GCU's College of Nursing and Health Care Professions has a nearly 35-year tradition of preparing students to fill evolving healthcare roles as highly qualified professionals.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Nationwide

Walden University

Earn your nursing degree from one of the largest nursing education providers in the U.S. Walden University’s BSN, MSN, post-master’s APRN certificate, and DNP programs are accredited by the Commission on Collegiate Nursing Education (CCNE). Get enhanced practicum support with our Practicum Pledge.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Nationwide, excluding CT, ND, NY and RI. Certain programs have additional state restrictions. Check with Walden for details.

Georgetown University

Georgetown University is one of the world’s leading academic and research institutions, and the School of Nursing has been delivering graduate nursing programs in a distance-learning environment since 2011. Georgetown's online programs allow students to learn from wherever they are while they pursue an accredited, mission-driven nursing education that will allow them to deliver high-quality care.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Nationwide, excluding NY and WA.

American Sentinel College of Nursing & Health Sciences at Post University

For more than 15 years, American Sentinel College of Nursing & Health Sciences at Post University has been educating registered nurses and healthcare professionals like you online. We offer a number of advanced online nursing degrees designed to give you the advanced education needed to achieve your personal and professional goals.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Natiowide except AZ, CA, DC, LA, NY, OR, TN, WA, PR

Top Online ACNP Programs

Our ranking criteria are based on factors such as tuition, acceptance rate, student-to-faculty ratio, and accreditation and use the latest and most robust U.S. government data sets, specifically the Integrated Postsecondary Education Data System (IPEDS) and College Scorecard.

School

Tuition

Program Length

Accreditation

Vanderbilt University

$1,997 per credit hour

3-4 hours

CCNE

Duke University

$2,166 per credit hour

2 years

CCNE

Herzing University

$755 per credit hour

24 months

CCNE

Drexel University

$1,134 per credit hour

3 years

CCNE

University of Connecticut

$1,200 per credit hour

2.5 years

CCNE

George Washington University

$1,530 per credit hour

3 years

CCNE

Case Western University

$2,308 per credit hour

2 years

CCNE

University of Virginia

$888-$1,450 per credit hour

21 months

CCNE

Widener University

$1,030 per credit hour

18-36 months

CCNE

Emory University

$2,082 per credit hour

4 semesters

CCNE

Tuition
$1,997 per credit hour
Program Length
3-4 semesters
Accreditation
CCNE
Online Options Available?
Yes

Vanderbilt offers one of the top acute care NP programs online nationwide. Students in this program can complete clinical rotations in their local areas or at Vanderbilt Medical Center in Nashville. While students complete most coursework online, the university also requires them to attend in-person intensives.

Vanderbilt students can attend different ACNP programs depending on their career and education goals. The university offers full and part-time Master of Science in Nursing (MSN) and Doctor of Nursing Practice (DNP) ACNP programs online. Students who have already completed an advanced nursing program can also pursue a post-MSN certificate through Vanderbilt.

Tuition
$2,166 per credit hour
Program Length
2 years
Accreditation
CCNE
Online Options Available?
Yes

Duke has over 2,000 clinical partners nationwide and internationally. These partnerships allow students to access an abundance of practicum sites and preceptors.

This program culminates in an MSN degree for those with an undergraduate degree. Advanced practice registered nurses (APRNs) may pursue Duke's post-graduate ACNP certificate program.

Tuition
$755 per credit hour
Program Length
24 months
Accreditation
CCNE
Online Options Available?
Yes

Herzing's 100% online ACNP program requires students to complete 48 credit hours and 585 clinical hours. The university offers six start dates annually, which allows students to keep working while they attend. 

The program culminates in an MSN degree and prepares students for the American Nurses Credentialing Center (ANCC) certification exam.

  • Application Deadline: Rolling
  • Contact Info: (888) 920-0937

Popular Online Adult-Gerontology Nurse Practitioner (AGNP) Programs

Sponsored
Purdue Global

Whether you’re taking the first steps toward a nursing degree, seeking to advance as a nurse or want to hone your craft with specialized study, there’s a path for you at Purdue Global’s School of Nursing. Our programs were designed so that you can easily balance your lives at home and work with school - without sacrificing the rigor and cutting-edge curriculum of a quality nursing education.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Nationwide, but certain programs have state restrictions. Check with Purdue for details.

Grand Canyon University

GCU's College of Nursing and Health Care Professions has a nearly 35-year tradition of preparing students to fill evolving healthcare roles as highly qualified professionals.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Nationwide

Walden University

Earn your nursing degree from one of the largest nursing education providers in the U.S. Walden University’s BSN, MSN, post-master’s APRN certificate, and DNP programs are accredited by the Commission on Collegiate Nursing Education (CCNE). Get enhanced practicum support with our Practicum Pledge.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Nationwide, excluding CT, ND, NY and RI. Certain programs have additional state restrictions. Check with Walden for details.

Chamberlain University

Chamberlain University is the #1 largest school of nursing with a community of more than 177,000 students, faculty, and alumni. Chamberlain offers BSN, MSN, and DNP programs online and has a long history of successfully delivering top quality education.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Nationwide

American Sentinel College of Nursing & Health Sciences at Post University

For more than 15 years, American Sentinel College of Nursing & Health Sciences at Post University has been educating registered nurses and healthcare professionals like you online. We offer a number of advanced online nursing degrees designed to give you the advanced education needed to achieve your personal and professional goals.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Natiowide except AZ, CA, DC, LA, NY, OR, TN, WA, PR

Tuition
$1,134 per credit hour
Program Length
3 years
Accreditation
CCNE
Online Options Available?
Yes

Philadelphia's Drexel University offers students direct access to some of the country's top healthcare systems. These connections are vital for students who need to find clinical placements and preceptors.

Upon completing the acute care nurse practitioner online program, Drexel students earn an MSN. Although most of the curriculum is online, students must attend several in-person intensives. So, living near the school and having reliable transportation is ideal.

Tuition
$1,200 per credit hour
Program Length
2.5 years
Accreditation
CCNE
Online Options Available?
Yes

Connecticut offers several online ACNP options, including a traditional MSN, a postgraduate certificate, and a BS to DNP. Because of its versatility, UConn is among the best acute care nurse practitioner schools online. It also extends the same faculty and services to online students and in-person attendees.

The university requires that students find their own clinical placements. They will work closely with the program director to find a successful match.

Tuition
$1,530 per credit hour
Program Length
3 years
Accreditation
CCNE
Online Options Available?
Yes

U.S. News & World Report ranked GWU's online ACNP programs as seventh in the nation. The university offers both an MSN and DNP pathway to becoming an acute care nurse practitioner. Students who enjoy high-intensity environments like intensive care units and emergency rooms will fit right in at GWU. 

Throughout the program, students must complete at least 650 hours of clinical experience with a university-approved preceptor. They must also attend some in-person experiences, including intensives and simulations, at the Washington, D.C., campus.

  • Application Deadline:
    • Priority: December 1st
    • Final: July 1st
  • Contact Info:
Tuition

$2,308 per credit hour

Program Length
2 years
Accreditation
CCNE
Online Options Available?
Yes

Case Western University's online acute care nurse practitioner program requires 39 credit hours of classes and 700 clinical hours. Before enrolling in the program, CWU requires students to accumulate at least one year of ICU experience.

Depending on their educational background, students can enroll in the MSN or postgraduate certificate ACNP program. The university also offers full—and part-time options to increase flexibility.

  • Application Deadline:
    • Spring: October 1st
    • Summer/Fall: March 15th
  • Contact Info:
Tuition

Resident: $888 per credit hour

Non-Resident: $1,450 per credit hour

Program Length
21 months
Accreditation
CCNE
Online Options Available?
Yes

UVA is ranked as one of the top public MSN programs nationwide. It offers full-time and part-time online acute care NP programs. The school also guarantees its alumni entrance into the program if they meet the admission criteria.

To earn their MSN degree, students in this program must complete a minimum of 500 clinical hours and 43-44 credit hours. The school also offers part-time options to increase flexibility and allow students to work while attending.

Tuition
$1,030 per credit hour
Program Length

MSN: 18-36 months

DNP: 24-36 months

Accreditation
CCNE
Online Options Available?
Yes

Widner offers a variety of options for students interested in earning an ACNP degree online. They can pursue an MSN or a terminal DNP degree with the addition of an extra year of study. Although this program's classes are online, students must attend one in-person health assessment lab in Chester or Harrisburg, PA.

  • Application Deadline: Rolling
  • Contact Info:
Tuition
$2,082 per credit hour
Program Length
4 semesters
Accreditation
CCNE
Online Options Available?
Yes

The online acute care NP program at Emory allows students to work while attending didactic courses from their homes. To earn an ACNP degree, they must complete 48 credit hours and 700 in-person clinical hours. 

Emory primarily offers this program as an MSN. However, students can pursue a more extensive and longer DNP option as well.

What to Expect in Online ACNP Programs

Admission Requirements

Admission requirements vary depending on the program, but generally, requirements include:

  • Registered nurse license
  • Program application
  • Bachelor of Science in Nursing degree from an accredited nursing program
  • Letter(s) of recommendation
  • Official transcripts
  • Resume/CV
  • Minimum GPA of 3.0 in previous coursework
  • Personal statement
  • Relevant clinical experience
  • College-level statistics course
  • GRE, if applicable
  • Interview, if applicable

Classes & Coursework

Specific classes vary depending on the school. However, all online acute care nurse practitioner programs require the same basic courses, including:

  • Advanced Pathophysiology
  • Advanced Pharmacology
  • Health and Physical Assessment
  • Ethics
  • Scientific Research
  • Health Policy
  • Advanced Nursing Roles in Health Care 
  • Foundation of Adult-Gerontology Acute Care 
  • Advanced Nursing Practice for Population-Based Care 

In addition to didactic courses, students must complete at least 500 in-person clinical hours with an approved preceptor.

How to Choose an Online ACNP Program 

Students should weigh several factors when choosing an online ACNP program. These include, but are not limited to:

  • Accreditation
  • Pass rate
  • Attrition rate
  • Tuition
  • Reputation
  • Private vs. public
  • Online vs. in-person

Popular Online Adult-Gerontology Nurse Practitioner (AGNP) Programs

Sponsored
Purdue Global

Whether you’re taking the first steps toward a nursing degree, seeking to advance as a nurse or want to hone your craft with specialized study, there’s a path for you at Purdue Global’s School of Nursing. Our programs were designed so that you can easily balance your lives at home and work with school - without sacrificing the rigor and cutting-edge curriculum of a quality nursing education.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Nationwide, but certain programs have state restrictions. Check with Purdue for details.

Grand Canyon University

GCU's College of Nursing and Health Care Professions has a nearly 35-year tradition of preparing students to fill evolving healthcare roles as highly qualified professionals.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Nationwide

Walden University

Earn your nursing degree from one of the largest nursing education providers in the U.S. Walden University’s BSN, MSN, post-master’s APRN certificate, and DNP programs are accredited by the Commission on Collegiate Nursing Education (CCNE). Get enhanced practicum support with our Practicum Pledge.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Nationwide, excluding CT, ND, NY and RI. Certain programs have additional state restrictions. Check with Walden for details.

Chamberlain University

Chamberlain University is the #1 largest school of nursing with a community of more than 177,000 students, faculty, and alumni. Chamberlain offers BSN, MSN, and DNP programs online and has a long history of successfully delivering top quality education.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Nationwide

American Sentinel College of Nursing & Health Sciences at Post University

For more than 15 years, American Sentinel College of Nursing & Health Sciences at Post University has been educating registered nurses and healthcare professionals like you online. We offer a number of advanced online nursing degrees designed to give you the advanced education needed to achieve your personal and professional goals.

Accreditation
CCNE
Location
Online
Prerequisite
RN Required

Enrollment: Natiowide except AZ, CA, DC, LA, NY, OR, TN, WA, PR

FAQs 

  • Is ACNP or FNP better?

    • Whether ACNPs or FNPs are better depends on your career goals and preferences. ACNPs generally work in hospital settings, specifically ICUs or ERs. FNPs work in primary care and care for pediatric to adult patients.
  • Can you switch from ACNP to FNP?

    • You cannot switch from ACNP to FNP unless you have passed the national certification exam as an FNP. The quickest way to go from an ACNP to an FNP is to earn a post-masters certificate. 
  • What is the difference between ACNP and AGACNP?

    • The primary difference between an ACNP and an AGACNP is the type of patients they treat. ACNPs treat patients with acute and complex medical conditions in critical care settings. AGACNPs care for patients with acute, chronic, and critical illnesses.
Kathleen Gaines
MSN, RN, BA, CBC
Kathleen Gaines
News and Education Editor

Kathleen Gaines (nee Colduvell) is a nationally published writer turned Pediatric ICU nurse from Philadelphia with over 13 years of ICU experience. She has an extensive ICU background having formerly worked in the CICU and NICU at several major hospitals in the Philadelphia region. After earning her MSN in Education from Loyola University of New Orleans, she currently also teaches for several prominent Universities making sure the next generation is ready for the bedside. As a certified breastfeeding counselor and trauma certified nurse, she is always ready for the next nursing challenge.

Education:
MSN Nursing Education - Loyola University New Orleans
BSN - Villanova University
BA- University  of Mary Washington

Expertise:
Pediatric Nursing, Neonatal Nursing, Nursing Education, Women’s Health, Intensive Care, Nurse Journalism, Cardiac Nursing 

Read More From Kathleen
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