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Watch First β€” Mitosis - Amoeba Sisters

Start with this short video, then scroll down for the full guide.

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Cell Cycle & Division

Why This Matters for Nursing: Cell division is essential for growth, healing, and tissue repair. Understanding the cell cycle helps you understand wound healing, cancer (uncontrolled division), and how chemotherapy drugs work.

What You Need to Know

The cell cycle is the series of events a cell goes through from one division to the next. There are two main types of cell division:

Type Purpose Result Where
Mitosis Growth, repair, replacement 2 identical daughter cells All body cells
Meiosis Sexual reproduction 4 genetically unique cells Egg and sperm cells

🧠 Memory Trick

IPMAT for Mitosis stages: Interphase (preparation) Prophase Metaphase Anaphase Telophase

"I Picked My Apples Today"

Mitosis = Makes Identical Twins (2 cells) Meiosis = Makes 4 (for reproduction)


The Cell Cycle

Interphase (90% of cell cycle)

The cell grows and prepares for division:

Phase What Happens
G1 (Gap 1) Cell grows; normal functions
S (Synthesis) DNA replicates (copies itself)
G2 (Gap 2) Cell prepares for division

M Phase (Mitotic Phase)

Actual division occurs: Mitosis + Cytokinesis

The Cell Cycle CELL CYCLE ~24 hours G1 Phase Cell grows (normal functions) S Phase DNA replicates (copies itself) G2 Phase Prepares for division Mitosis P-M-A-T (4 stages) Cyto- kinesis Cell splits β†’ 2 cells Interphase (G1 + S + G2) = ~90% of cycle M Phase (Mitosis + Cytokinesis) = ~10%

Mitosis: Cell Division

Prophase

  • Chromosomes condense (become visible)
  • Nuclear membrane breaks down
  • Spindle fibers form

Metaphase

  • Chromosomes line up in the middle
  • "M for Middle"

Anaphase

  • Chromosomes pull apart to opposite poles
  • "A for Apart"

Telophase

  • Two new nuclei form
  • Nuclear membranes reform
  • "T for Two"

Cytokinesis

  • Cytoplasm divides
  • Results in 2 identical daughter cells

Mitosis vs. Meiosis

Feature Mitosis Meiosis
Purpose Growth, repair Reproduction
Starting cells 1 1
Ending cells 2 4
Genetic content Identical to parent Half of parent (unique)
Chromosome number Same (diploid→diploid) Halved (diploid→haploid)
Divisions 1 2
Occurs in All body cells Sex cells only

Chromosome Numbers

  • Diploid (2n): Full set of chromosomes (46 in humans)
  • Haploid (n): Half set (23 in human egg/sperm)

When egg (23) + sperm (23) combine β†’ zygote (46)


✏️ Worked Examples

Example 1: Identify the Stage

Description: Chromosomes are lined up in the center of the cell.

Step 1 β€” Identify the key action. The key word is "lined up in the center." Which phase does that describe?

Step 2 β€” Use your memory trick. M = Middle. The phase where chromosomes march to the middle of the cell is Metaphase. It's like the chromosomes are lining up for inspection before being pulled apart.

Answer: Metaphase


Description: Sister chromatids are being pulled to opposite ends.

Step 1 β€” Identify the action. "Being pulled to opposite ends" = chromosomes separating, moving away from each other toward opposite poles of the cell.

Step 2 β€” Use the memory trick. A = Apart. The phase where chromosomes are pulled Apart to opposite poles is Anaphase. Think of the "A" arms of the letter A pointing outward β€” the chromosomes are splitting to the sides.

Answer: Anaphase


Example 2: Step-by-Step Solution

To solve this type of problem, start by identifying the key values given in the question. Then apply the formula we covered above...

Step 1: Convert the mixed number to an improper fraction...

Step 2: Find the common denominator between the two fractions...

Keep reading β€” there's more to this guide

The worked examples and practice problems are the part that actually prepares you for the TEAS.

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